Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. Not what people like me are saying. This website is for information purposes only. 500+ pages of Natural Medicine Alternatives and Information. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. Asesora y Consultora Web3 para empresas. Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. This is a horrible disease that ravages the body. The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. Acta Endocrinol 1988, 118:460464. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Increased sensitivity to cold. Oops I have just bought my first jar of marmalade in over ten years! Overtreatment, of course, is the hallmark danger of overdiagnosis. It does not seem to quantify the increased risk, and it keeps saying it is hyperthyroidism that causes the oxidised stress. Sayer Ji is the founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, and SteeringCommittee Memberof the Global Non-GMO Foundation. They only reappear when I need to fine tune the medication. by D.ap Tue Feb 21, 2017 10:40 am, Powered by phpBB Forum Software phpBB Limited. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Privacy Policy. But I for one, do appreciate anything that other members forward about potential links, causes, aids to healing, whatever you can them. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related diseases.. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Si as lo deseas puedes revisar el resto de nuestros contenidos para encontrar lo que buscabas o directamente utilizar nuestro buscador. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. A place for patients and relatives. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". Different strokes for different folks for sure! In 2011 I switched docs and was put on Armour as he told me Synthroid and the like are poison and they do not work. However, that information will still be included in details such as numbers of replies. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. I discovered this article published in Wakeup World. Endocrinology 2008, 149:22412250. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. Also this study finds no link with breast cancer, when others have found a link. Article published in Wakeup-World.Com. If people do not wish to find out all they can about their disease that is fine too. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. Increased sleepiness. [5] Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5' deiodinase in lung cancer with peripheral lung tissues. J. Clin. The authors expanded on their findings further: "However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. As a never smoker I truly wish I smoked so I could just say that's why I got this. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. 2004 Jun;9(2):157-79. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Endocrinology 2008, 149:22412250. Capmatinib (Tabrecta) is the first FDA-approved MET-targeting medication for treating metastatic NSCLC. Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). I have so much to say about this I could write a book. Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. Patient characteristics. They compared sale of, "However, the impression we get from our experience, Health, Studies, Supps & Pharmaceuticals. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. All the more reason to prescribe T3, I say! I think part of sharing information here on Inspire is the discussions about the articles we share. I was sure that the paper had been discussed here shortly after publication in 2013, but cannot find the thread! Unfortunately, it's quite typical. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. But what can be done for patients who are at low (February 2002). [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.Altern Med Rev. Symptoms. Baked or Fried avocado fries [Vegetarian]. I very much appreciate the information you shared. Post Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. In comparison, 62.4% of female and 37% of male . Other factors that can trigger thyroid problems include: autoimmune diseases like Hashimoto's or Graves' disease; thyroid surgery; radiation treatments to the neck or upper chest; and certain medications, including interferon alpha and interleukin-2 cancer medications, amiodarone . Physician/Author on Facebook. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. Endocrinology 1985, 117:12011208. Thyroid disease is a major public health concern worldwide. What I am personally saying issince I personally have a disease that may kill me, I sure as heck have every right to find out ALL I can about it. Thus, I am monitored carefully. Forgot account? In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. millions treated for hypothyroidism at risk for lung cancer. The study included more than 128,000 veterans aged 18 to 26 and found that, just 30.2% of females and 18.7% of males had received HPV vaccination. Another recently approved drug is tepotinib (Tepmetko). Even in the mildest form, hypothyroidism affects the heart. http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-l Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, Iodine Supplementation Support by VWT Team. [13] Hollowell JG, Staehling NW, Flanders WD, et al. Keep checking back for the register link to appear. [4], DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. I can understand why tennis 123 wrote, "I have so much to say about this I could write a book". Are you sure you want to block this member? Non-small cell lung cancer is the most common type of lung cancer, accounting for about 81% of all cases. Thanks, I am not suggesting I believe in all that I see. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be.". Is This the Real Reason You're Exhausted All the T Why An Alkaline Approach Can Successfully Treat Ca We're Losing the War on Cancer- Here's Why. Why not simply call it selenium deficiency? Log In. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Post by D.ap Tue Feb 21, 2017 6:40 pm "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and . [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. [13] Hollowell JG, Staehling NW, Flanders WD. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. I am going to go for a walk with my dog :)). Iodine - and the lack of it - is implicated in breast cancer, after all. END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called active ingredient T4 versus the natural variations in hormone concentrations found in the real thing, which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. Brit Med J 1978, 1:210212. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion You may not notice signs or symptoms of the disease. I have no further scientific evidence. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. This is a news report of the research, so I can't learn the details of how the science was conducted. According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called 'subclinical' hypothyroidism only detected via blood work. In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. Compared to patients without hypothyroidism, those with a high TSH level before hospitalization stayed in the hospital 1.2 days longer and had a 49% higher risk of 30-day readmission and a 43% . Or that it was the many years of not being diagnosed with hypothyroidism, courtesy of daft blood test ranges, before finally tipping a TSH over 5 (or even 10) before treatment is commenced, by which time the damage is done. It took over five years before the someone figured out my ongoing symptoms were due to hypothyroidism. Correlation is when two things seem to happen at the same time, in the same place, and/or in the same population. MASA Traditional Tortilla Chips by Ancient Crunch, Vitamins, Minerals & Amino Acid Supplements, http://www.greenmedinfo.com/blog/study- ng-cancers, Patients' Perspectives On Refusing Diagnosis Or Treatment For Lung Cancer, Unintended Weight Loss Is The 2nd Highest Risk Factor For Certain Cancers, Stress Causes Genetic Mutations; Cancer Thrives Under Stress, Tetracyclines (and A Few Other Antibiotics) As A Cure For Cancer, Vitamin B May Increase Risk Of Lung Cancer In Men, Study Says, Biggest Study So Far Shows Aspirin Reduces Any Cancer Risk, Methylation Levels Can Predict Breast Cancer Risk, Vitamin A As A Powerful Treatment For Cancer, Screening For Testicular Cancer (a Review), For Many Cancers Early Diagnosis Can Actually Be Deadly, As Altitude Rises, Lung Cancer Rates Fall, The Anti Depression Pills that may Kill Cancer, Holy Grail Blood Test May Detect Cancer Before Tumors Form. Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. View the data on our Hypothyroidism Research page. bear in the big blue house characters; colne times obituaries this week Menu Toggle. In my opinion, the science of the study doesn't support the conclusion. If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. However, I do not believe it was out of the blue now. 1). PMID: 11929079, [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. My Endocrinologist was, and continues to be, open about the elevated risk for thyroid cancer due to the multiple. Patients with incomplete information (n = 127), preexisting hypothyroidism or levothyroxine replacement before initiation of ICI therapy (n = 11), or other factors known to contribute to thyroid dysfunction after immunotherapy (n = 17) were excluded (Fig. Factors found to be associated with mortality were age, senile dementia, congestive heart failure, chronic renal failure, and a history of cerebrovascular disease. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore back up causing excessive T4 activity, i.e. Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM. I had doctor after doctor tell me it was in my head or I was menopausal. Yet Another Frankenfood Pandoras Box: the Majorit How Medical Science Proves that Black Is White. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Just go on one of the thyroid sites and read the stories. Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. There are several books out there written about the topic. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. Share your experience, learn from others. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). J Endocrinol Invest. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. I cried with joy when I found out there was something really wrong with me. Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. J Exp Biol 2010, 213:28992911. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. Data sources: The Medline and Cochrane Library electronic databases . Non-ASPS articles which could be relevant. LOL. Hypothyroidism reduces respiratory drive and can cause obstructive sleep apnea or pleural effusion, while hyperthyroidism increases respiratory drive and can cause dyspnea on exertion. Thank you for bringing it to our attention. Due to excessive bot signups along with nefarious actors we are limiting forum registration. Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to replacement therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' See more of Keri Topouzian, D.O. Ultimately, this Italian study brings further attention to one of a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. I invite those interested to read it and perhaps we can have a discussion on this study. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as hypothyroidism? Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. The American Lung Association connects patients, families, friends and caregivers for support and inspiration as they face lung cancer. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. As I am the caregiver for my dad who has Stage IV lung Cancer, I hope more research can be done on this topic soon. LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. Also, what is oxidised stress??? Article published in Wakeup-World.Com. 2002 Feb ;25(2):106-9. Clin Cancer Res 2011, 30:77. Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function.