The limited usefulness of agents of this class, including Phentermine, [see Clinical Pharmacology (12.1, 12.2)] should be measured against possible risk factors inherent in their use such as those described below. Phen Caps is recommended by over 30,000 people like you who want to lose weight fast and effectively without the drawbacks of prescription medications. Phentermine hydrochloride USP is a sympathomimetic amine anorectic. I hold a DEA cert. Selling or giving away Phentermine may harm others and is against the law. It is impossible for them to complete the necessary physical evaluation (and follow-up) that is required to ensure that phentermine will not cause you undue harm. 1 Here are the results of a recent poll that asked current phentermine patients where they received their phentermine prescription ( Doctors often prescribe a dose of 5-HTP and vitamin B12 with a Phentermine prescription in order to enhance its effects and to relieve some side effects. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. It helps patients lose weight by suppressing their appetite and boosting their energy levels, thus leading to a more active lifestyle and greater calorie burn. Required fields are marked *. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Diabetes & Metabolism Journal. The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. Adults and children 17 years of age and older15 to 30 milligrams (mg) once a day, taken at approximately 2 hours after breakfast. (2019, May 03). Phentermine.com is a property of: Careworld LLC. More, these sites also operate pharmacies that are not VIPPS-accredited, so you may also be putting your personal information and or money at-risk ( Patients must be instructed on how much Phentermine to take, and when and how to take it [see Dosage and Administration (2)]. Generic name: Phentermine hydrochloride Tablets: 37.5 mg phentermine hydrochloride, USP (equivalent to 30 mg phentermine base). 2 It isnt prescribed on request, but rather when a healthcare provider notices it may be beneficial for a specific patient to lose weight in order to improve their overall health or to decrease the risk of certain health concerns. Perreault L. Obesity in adults: Drug therapy. In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg Phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg Phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of Phentermine. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Metabolism Phentermine has two metabolic pathways; hydroxylation and oxidation. Click here for an email preview. After the tablet has melted, swallow or take a sip of water. By using the site you agree to our Privacy, Cookies, and Terms of Service Policies. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Animal reproduction studies have not been conducted with Phentermine. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. A doctor that sees you regularly is in a unique position to assess the pros and cons of a phentermine prescription because he/she is familiar with your medical history, as well as other medications, allergies, and weight trends over time. Use of Phentermine is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis. the unsubscribe link in the e-mail. All rights reserved. With more than 4 million prescriptions written in the United States each year, phentermine is an undeniably popular weight loss medication ( If not, additional education or an additional certification may be needed. Clinics specializing in weight loss often employ bariatric specialists who have additional training in obesity management. x\8zS wU^TM;J`Kc=@y\} Blf\3K|xL?D$aesY"_(ceD!s!@P,?K&Bd8cKS~zq=7'kiw\dqL:A ?O0O@+}y"z[?Os/Kht;[SN4h9c31{8Eh7dPc\BFE(e&9;!PUqK\aD 7) &\1!j-_Y7jD,Sp)AWc/igg?v{5\%a'd9"D0=gRGEZgpbMQJD *k*;1'w24w, d r d?&8xeEj`\2C6xrhq2@-{P5CbBL(/0m8&8Ltnvf};y852q*+I%l=+rwGUv*:!80|>tb?U?L,zG8%K`n]+:,LCE")Xz\^):{~{=vu=Qg`A\6qT=WCZ TcR%mi,OV_RtK1e&:By~i~!nu (1/19/2016) Ohio Strenthens Opioid Prescribing Guidlines to Further Prevent Prescription Drug Abuse and Save . The drug is classified under a certain chemical class known as amphetamine as it has a similar pharmacology value to other drugs classified in the class. What to offer the 99% of patients with severe obesity who do not undergo bariatric surgery? %PDF-1.6 % Get the best fitness, food, and weight loss tips to succeed on your journey! It is important not to perform activities that require a patient to be alert while experiencing mental impairment as an adverse effect. As a reminder, Ohio law requires physicians who prescribe any controlled substances, not just opioids, to submit an ICD-10 code with that prescription. However, it caused a chronic condition known as pulmonary hypertension, which led to the death of many patients. Dispense in a tight container as defined in the USP, with a child-resistant closure (as required). In 1968, three years after its release, Aminorex was withdrawn. The possibility of an association between PPH and the use of Phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken Phentermine alone. 4 0 obj 138 0 obj <>stream Portions of this document last updated: Feb. 01, 2023. If you are a Mayo Clinic patient, this could Manifestations of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Place the tablet on the top of your tongue right after removing it from the bottle. U.S. Food and Drug Administration. You may opt-out of email communications at any time by clicking on iQJG\If6CuoG^|&qXegM,+vmC [To w{`F@kMxVBrH7.1g B;H _BfHPXK#Q Phentermine has not been studied in patients with eGFR less than 15 mL/min/1.73m2, including end-stage renal disease requiring dialysis; avoid use in these populations. If we combine this information with your protected Phentermine was later provided to patients in combination with dexfenfluramine and fenfluramine as a more powerful appetite suppressant that could also act as a fat burner. Or it can help you feel full longer. These are both major barriers to optimal medical care. The following information includes only the average doses of this medicine. 2019; doi:10.1016/j.mayocp.2018.11.020. To provide you with the most relevant and helpful information, and understand which The drug is always accompanied by increased physical activity and a diet that includes a lower amount of calories. Before taking phentermine, tell your doctor and pharmacist if you are allergic to phentermine, any other medications, or any of the ingredients in phentermine tablets. Not only can losing weight harm an unborn baby during pregnancy, but the drug may also cause adverse effects. Package insert / product label Common side effects of phentermine include: Phentermine is one of the most prescribed weight-loss medicines. In addition to its function as an appetite suppressant, Phentermine drugs also act as energy boosters. Phentermine is a popular prescription drug that is often used to treat obesity. As much as 33% of the U.S. adult population are considered to be obese. A reduction in insulin or oral hypoglycemic medications in patients with diabetes mellitus may be required. Phentermine is for people with obesity or overweight who haven't been able to lose enough weight with diet and exercise alone to improve their health. The drug is mainly an appetite suppressant, thus making a patient feel fuller after (and between) meals and making the patient more likely to consume foods that have lower amounts of calories. 1558 0 obj <>/Filter/FlateDecode/ID[<7182559B062CF74D9CEE71C953F61692>]/Index[1530 62]/Info 1529 0 R/Length 121/Prev 89015/Root 1531 0 R/Size 1592/Type/XRef/W[1 2 1]>>stream ). Patients must be informed that Phentermine hydrochloride is a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity, and that coadministration of Phentermine with other drugs for weight loss is not recommended [see Indications and Usage (1) and Warnings and Precautions (5.1)]. It is freely soluble in water; sparingly soluble in warm alcohol, insoluble in chloroform, acetone, ether and benzene. While this drug may sound like a wonder pill, patients should ensure they know are familiar with the precautions, interactions, side effects and other important details before they start taking it. OSMA has historically had concerns with the limitations that these rules place on physicians who treat patients with obesity. Tak YJ, et al. Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. It is often prescribed to be taken in the morning, before or after breakfast. Phentermine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly. Taking more than the prescribed amount of Phentermine can lead to an overdose, which means if a patient misses a dose, they should never try to make up for it by taking more than the prescribed amount at the next dose. The goal of the drug is to help patients lose weight and increase energy since the withdrawal symptoms of include fatigue and weight gain through an increase in appetite, the product is rendered a waste of the patients time and money. The medical board would like to work with the pharmacy board to make OARRS reports more available and helpful to physicians. While discussing the use of Phentermine with the doctor, a patient is provided a list of lifestyle changes to implement while using this product. Follow your doctor's orders or the directions on the label. 104 0 obj <> endobj Since it may lead to such symptoms, it also has the potential to cause severe withdrawal symptoms, especially when a patient goes cold turkey.